Posted on 24 Agustus 2015 by admin
New Vaccine to Treat HIV / AIDS
ROAD long fight against HIV / AIDS back to optimism. Wednesday (18/2) and then, The Scripps Research Institute (TSRI), Florida, USA, announced a new projected vaccine could be used to ward off bullies viruses that the human immune system.
The study stated that they develop AIDS drugs capable of handling the HIV virus, and claimed to be more potent than other antibodies.
Scientists tested a vaccine prototype named eCD4-Ig. They created the AIDS virus specifically for animals. Then injected vaccines to macaque monkeys who became a guinea pig.
As a result, the system is able to work effectively protection against any organism HIV-1, HIV-2 and SIV (simian immunodeficiency virus) virus even with high doses of injected repeatedly.
ECD4-Ig vaccine is an expression (imitation) consisting of the receptor cells and serves as a deterrent. These cells are white blood cells that play a role in helping the body fight infection and keep the body's immunity.
The study, funded by the US National Institute of Allergy and Infectious Diseases (NIH) continued the previous molecule discovery, namely the CCR5 receptor. The team developed a receptor imitation through the experiment for 40 weeks.
"We have succeeded in developing appropriate expression to prevent and catch the virus," said Matthew Gardner, TSRI researchers are also the main author of the research report.
Furthermore, the security level of the prototype still needs to be tested. "We need to do further studies related to the safety aspects of vaccines, both in macaque monkeys and humans,"
Efforts to create an HIV vaccine is one long struggle against the AIDS epidemic, which first appeared in 1981 in the US. Previously, several candidate vaccines failed to evolve and mutate. The first trial in 1987 did not produce a potent vaccine.
RV144 vaccine, which was developed six years ago, was able to reduce the risk of AIDS infection in 16 thousand patients in Thailand. Nevertheless, the success rate of 32% drug still deemed inefficient.
Antiretroviral drugs, were discovered in the 1990s, only able to take care but can not treat or prevent the virus. Since 1981 until now, there were 78 million people infected with HIV in the world. The UN agency noted that the epidemic has killed 39 million people.
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